The Most Commonly Prescribed drugs are of our time safe?
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How do Statins Work? The Process of Producing cholesterol begins with a two carbon molecule, acetyl-CoA, known as the "building blocks of life." Acetyl-CoA molecules combine to form hydroxymethyl glutaric acid (HMG). The HMG-CoA reductase enyme is required to be produced from Mevalonate for HMG-CoA reductase. Statin drugs inhibit this enzyme and That Is Why They are known as HMG-CoA reductase inhibitors. This is the reason for the reported Numerous side effects.
Statin drugs do not just inhibit the production of cholesterol. Statins inhibit the production of an intermediary Entire group of enzymes and molecules have essential biochemical functions That. The Mevalonate chain end products and 3 Produces One Of Those is Cholesterol. Ubiquinone and dolichol are the others.
Also known as ubiquinone Co-Enzyme Q10 is an essential cellular nutrient formed in the mitochondria and is Necessary for ATP production, Functioning as an electron transporter cytochrome oxidase to, the primary respiratory enzyme. High levels of Co-Q10 are required by the heart to function. Ubiquinone, in the form of Co-Q10 is in all cell membranes where it plays a vital role in cell membranes Maintaining proper structure for nerves and muscles to function. Ubiquinone reduction in serum levels after statin therapy Have Been Described. (Mabuchi H, et al, J Thromb Atherosclero. 2005; 12 (2): 111-9)
Studies have shown That the use of statin agents for cholesterol control will reduce the level of co-enzyme q-10 by up to 40%. It Appears That These statin agents, membrane function by Altering Also Actually impair transport energy to muscles These Necessary to Keep Them Functioning properly. Co-Q10 deficiency can cause muscle wasting, weakness and pain and heart failure (the heart is a muscle!).
Proteins are synthesized Within the endoplasmic reticulum of the membranes. This creation of complex peptides is directed by dolichol phosphate. Also critical are the Dolichols in the assembly of glycoproteins, which effectively allow complex structures to protein fold and interact with receptors and membranes. Dolichol-mediated processes create complex neuropeptides, and Mechanisms Critical cellular communication, identification, and immune function. The reality of Dolichol inhibition by statin agents is evident in the turmoil and the Resultant cellular function is not unexpected. Also it is not unexpected and abnormal cognition That altered behavior can result from statin induced neuropeptide formation.
Another common side effect Associated with statin agents When used to Dramatically reduce cholesterol levels are the degenerative type diseases, Almost like Lou Gehrig's disease or multiple sclerosis, and this is Because there is damage to the cellular membranes That make up the insulation around the nerves. It is like electrical wiring in an old house where the insulation around the wire has broken down leaving Exposed wiring. These poorly Functioning nerves and muscle membranes result in Aches / pains as well as Decreased Decreased strength and nerve function. Memory and Thought Process May Also be severely affected.
Drastic Cholesterol Reduction. It Seems That A Lot Of These problems begin When elevated cholesterol levels and aggressive reduction Become Occurs with the use of statin agents. Therefore elevated cholesterol levels Have Been Described as the initiating phase in the development of atherosclerosis. Of course, statins inhibit the production of cholesterol - they do this very well. Cholesterol is the body's repair substance: scar tissue contains high levels of cholesterol, scar tissue in the arteries Including. Cholesterol is the precursor to vitamin D, Numerous biochemical processes Including Necessary for mineral metabolism. The use of statin agents will reduce the synthesis of Vitamin D. Studies have Identified the Increased incidence of musculoskeletal pain in Patients who are vitamin D deficient, and results in a dramatic improvement That replacement. (Al Faraj S, et al. Vitamin D Deficiency and chronic low back pain in Saudi Arabia, "Spine 2003; 28 (2): 177-9).
A number of Patients describe and diarrhea Gastrointestinal Symptoms Associated with statin therapy. Unfortunately after an Extensive gastrointestinal workup, the statin therapy is not discontinued. Statin agents reduce bile salts production, which effectively is required for the digestion of fat. Those Who Suffer from Low Cholesterol Often have trouble digesting fats. Also functions as a cholesterol Powerful antioxidant, Thus Protecting Us Against Cancer and Aging.
It is no surprise That the aggressive control of cholesterol, statin therapy typical of, in an attempt to reduce cardiovascular disease in Itself Produces it's own disease process. Even though statins have proven to decrease not Been The Risk of heart attacks and strokes For Those not suffering from heart disease.
Gary Stanton, Holistic Nutritionist and Natural Health advocate and Robert Carlson, MD, FACS, board certified in General and Thoracic Surgery, participated in a cardiovascular research at Harvard University and is a Fellow of the American College of Surgeons. He received "America's Top Doctor Award" Cardiothoracic surgery in 2003 and in 2007. Dr. Carlson is Also a Medical Advisor to New Health Corp. http://www.heartsavior.com Tel: 1-877-263-3555
Article Source: Are The Most Commonly Prescribed drugs of our time safe?
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